ISSN 1662-4009 (online)

ey0019.11-9 | New predictors of obesity development | ESPEYB19

11.9. Fat mass and fat-free mass track from infancy to childhood: New insights in body composition programming in early life

IA van Beijsterveldt , KS de Fluiter , LM Breij , M van der Steen , ACS Hokken-Koelega

joelh@broadinstitute.org Obesity (Silver Spring). 2021 Nov;29(11):1899–1906. doi: 10.1002/oby.23271. Epub 2021 Sep 21. https://pubmed.ncbi.nlm.nih.gov/34549538/Brief Summary: This longitudinal study assessed body composition in a cohort of children at ages 1, 3, and 6 months and 4 years (n...

ey0015.4-3 | Important for clinical practice | ESPEYB15

4.3 Cardiovascular risk factors and carotid intima media thickness in young adults born small for gestational age after cessation of growth hormone treatment: a 5-year longitudinal study

M van der Steen , GF Kerkhof , CCJ Smeets , ACS Hokken-Koelega

To read the full abstract: Lancet Diabetes Endocrinol 2017;5:975-985Whereas most SGA children experience spontaneous catch-up growth leading to the achievement of normal adult height, approximately 10% remain short and are candidates for GH therapy. SGA subjects have increased cardio-metabolic disease risk [17] and the effects of GH treatment on blood...

ey0020.2-4 | Important for Clinical Practice | ESPEYB20

2.4. Childhood growth hormone treatment and metabolic and cardiovascular risk in adults born small for gestational age after growth hormone cessation in the Netherlands: a 12-year follow-up study

WJ Goedegebuure , M van der Steen , CCJ Smeets , ACS Hokken-Koelega

Brief summary: In this longitudinal study, the authors investigated the metabolic and cardiovascular health profile of 167 adults born SGA and previously treated with rhGH during a period of 12 years after therapy discontinuation. No relevant differences were found in treated SGA subjects compared with untreated SGA adults or adults born appropriate for gestational age (AGA), thus suggesting long-term metabolic and cardiovascular safety of rhGH treatment in short SGA children....